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Daniel T Connolly Selected Research

APD791

6/2010Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): a highly selective 5-hydroxytryptamine2A receptor inverse agonist for the treatment of arterial thrombosis.

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Daniel T Connolly Research Topics

Disease

5Flushing
08/2012 - 12/2006
3Atherosclerosis
06/2007 - 12/2006
2Thrombosis (Thrombus)
06/2010 - 05/2008
1Dyslipidemias (Dyslipidemia)
04/2012
1Myocardial Infarction
01/2012

Drug/Important Bio-Agent (IBA)

7Niacin (Nicotinic Acid)FDA LinkGeneric
08/2012 - 12/2006
2ProstaglandinsIBA
08/2012 - 12/2006
2LipidsIBA
04/2012 - 10/2008
2HDL CholesterolIBA
10/2008 - 06/2007
2Prostaglandin D2IBA
08/2008 - 06/2007
1GTP-Binding Proteins (G-Protein)IBA
01/2012
1APD791IBA
06/2010
15-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
06/2010
1Serotonin (5 Hydroxytryptamine)IBA
06/2010
1Nonesterified Fatty Acids (NEFA)IBA
10/2008
1LDL CholesterolIBA
10/2008
13- (1H- tetrazol- 5- yl)- 1,4,5,6- tetrahydrocyclopentapyrazoleIBA
10/2008
1Triglycerides (Triacylglycerol)IBA
10/2008
1AR 246686IBA
05/2008
1Mitogen-Activated Protein KinasesIBA
06/2007
1pyrazoleIBA
06/2007
1Prostaglandins DIBA
12/2006